Improving healthcare with light and sound
PUBLICATIONS
2024
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Mengjie Shi, Tom Vercauteren, and Wenfeng Xia. "Learning-based sound speed estimation and aberration correction for linear-array photoacoustic imaging." Photoacoustics doi: 10.1016/j.pacs.2024.100621 [PDF]
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Mengjie Shi, Tom Vercauteren, Wenfeng Xia, "Learning to compensate spectral coloring in a LED-based photoacoustic/ultrasound imaging system", Photons Plus Ultrasound: Imaging and Sensing 2024 doi: 10.1117/12.3000523 [PDF]
2023
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Mengjie Shi, Tom Vercauteren, Wenfeng Xia, "Learning-based sound-speed correction for dual-modal photoacoustic/ultrasound imaging", 2023 IEEE International Ultrasonics Symposium (IUS) doi: 10.1109/IUS51837.2023.10307082 [PDF]
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T. Zhao, T. T. Pham, C. Baker, M. T. Ma, S. Ourselin, T. Vercauteren, E. Zhang, P. C. Beard, W. Xia. "All-optical multimode fibre photoacoustic endomicroscopy with scalable spatial resolution and field-of-view", SPIE Opto-Acoustic Methods and Applications in Biophotonics VI Aug 2023 doi: 10.1117/12.2670411 [PDF]
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Patent application: Wenfeng XI, Tianrui ZH, Vercauteren T, Ourselin S, inventors; Kings College London, assignee. Apparatus and method for spatial light modulation. United States patent application US 17/792,914. 2023, Jul 27 2023
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Mengjie Shi, Tom Vercauteren, Wenfeng Xia, "Learning-based sound speed reconstruction and aberration correction in linear-array photoacoustic/ultrasound imaging", arXiv preprint, arXiv:2306.11034 [PDF]
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T. Zhao, M. Shi, S. Ourselin, T. Vercauteren, W. Xia, "Deep learning boosts the imaging speed of photoacoustic endomicroscopy", SPIE Photons Plus Ultrasound: Imaging and Sensing. Mar 2023. doi: 10.1117/12.2649088 [PDF]
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Mengjie Shi, Semyon Bodian, Simeon J West, Sanjayan Sathasivam, Ross J Gordon, Paul Collier, Tom Vercauteren, Adrien E Desjardins, Sacha Noimark, Wenfeng Xia, "Visualisation of medical needles using photoacoustic imaging with candle soot composites coatings and deep learning", SPIE Photons Plus Ultrasound: Imaging and Sensing. Mar 2023. doi: 10.1117/12.2648775 [PDF]
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Mengjie Shi, Tom Vercauteren, Wenfeng Xia, "Spatiotemporal SVD for denoising in LED-based photoacoustic imaging", SPIE Photons Plus Ultrasound: Imaging and Sensing. Mar 2023. doi: 10.1117/12.2648825 [PDF]
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Christian Baker, Weidong Liang, Mengjie Shi, Tianrui Zhao, Francois Joubert, Sebastien Ourselin, Tom Vercauteren, Richard Colchester, Simeon West, Adrien Desjardins, Wenfeng Xia,"Real-time 3D-photoacoustic tracking system for localisation of an intraoperative needle tip", Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI. Mar. 2023. doi: 10.1117/12.2650170 [PDF]
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Christian Baker, Miguel Xochicale, Francois Joubert, Fang-yu Lin, Sunish Mathews, Dzhoshkun I Shakir, Sebastien Ourselin, Anna David, Brian Dromey, Adrien Desjardins, Tom Vercauteren, Wenfeng Xia,"Real-time ultrasonic needle tip tracking with an integrated fibre-optic hydrophone", Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI. Mar. 2023. doi: 10.1117/12.2650092 [PDF]
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E. Maneas, A. Hauptmann, E. J. Alles, W. Xia, S. Noimark, A. L. David, S. Arridge, A. E. Desjardins, "Enhancement of instrumented ultrasonic tracking images using deep learning", International Journal of Computer Assisted Radiology and Surgery. Feb. 2023. doi: 10.1007/s11548-022-02728-7 [PDF]
2022
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T. Zhao, M. Zhang, S. Ourselin, and W. Xia, “Wavefront shaping-assisted forward-viewing photoacoustic endomicroscopy based on a transparent ultrasound sensor” Applied Sciences, vol. 12, no. 24, p. 12619, Dec. 2022. doi: 10.3390/app122412619 [PDF]
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M. Shi, T. Vercauteren, and W. Xia, “Spatiotemporal singular value decomposition for denoising in photoacoustic imaging with a low-energy excitation light source” Biomedical Optics Express, vol. 13, no. 12, p. 6416, Nov. 2022. doi: 10.1364/boe.471198 [PDF]
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C. Baker et al., “Intraoperative needle tip tracking with an integrated fibre-optic ultrasound sensor,” Sensors, vol. 22, no. 23, p. 9035, Nov. 2022. doi: 10.3390/s22239035 [PDF]
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E. Maneas, A. Hauptmann, E. J. Alles, W. Xia, S. Noimark, A. L. David, S. Arridge, and A. E. Desjardins, “Enhancement of instrumented ultrasonic tracking images using deep learning” International Journal of Computer Assisted Radiology and Surgery, vol. 18, no. 2, pp. 395–399, Sep. 2022. doi: 10.1007/s11548-022-02728-7 [PDF]
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M. Shi, S. Bodian, S. J. West, S. Sathasivam, R. J. Gordon, P. Collier, T. Vercauteren, A. E. Desjardins, S. Noimark, and W. Xia, “Enhanced photoacoustic visualisation of clinical needles by combining interstitial and extracorporeal illumination of elastomeric nanocomposite coatings” Sensors, vol. 22, no. 17, p. 6417, Aug. 2022. doi: 10.3390/s22176417 [PDF]
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T. Zhao, T. T. Pham, C. Baker, M. T. Ma, S. Ourselin, T. Ver- cauteren, E. Zhang, P. C. Beard, and W. Xia, “Ultrathin, high-speed, all-optical photoacoustic endomicroscopy probe for guiding minimally invasive surgery” Biomedical Optics Express, vol. 13, no. 8, p. 4414, Jul. 2022. doi: 10.1364/boe.463057 (Editor's Pick) [PDF] [Optica News Release]
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M. Shi, T. Zhao, S. J. West, A. E. Desjardins, T. Vercauteren, and W. Xia, “Improving needle visibility in LED-based photoacoustic imaging using deep learning with semi-synthetic datasets” Photoacoustics, vol. 26, p. 100351, Jun. 2022. doi: 10.1016/j.pacs.2022.100351 [PDF]
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T. Zhao, M. T. Ma, S. Ourselin, T. Vercauteren, and W. Xia, “Video-rate dual-modal photoacoustic and fluorescence imaging through a multimode fibre towards forward-viewing endomicroscopy,” Photoacoustics, vol. 25, p. 100323, Mar. 2022. doi: 10.1016/j.pacs.2021.100323 [PDF]
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S. J. Mathews et al., “Ultrasonic needle tracking with dynamic electronic focusing” Ultrasound in Medicine & Biology, vol. 48, no. 3, pp. 520–529, Mar. 2022. doi: 10.1016/j.ultrasmedbio.2021.11.008 [PDF]
2021
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C. Baker et al., “Real-time ultrasonic tracking of an intraoperative needle tip with integrated fibre-optic hydrophone,” in 2021 IEEE International Ultrasonics Symposium (IUS). IEEE, Sep. 2021. doi: 10.1109/ius52206.2021.9593381 [PDF]
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M. Shi, Z. Wang, T. Zhao, S. J. West, A. E. Desjardins, T. Vercauteren, and W. Xia, “Enhancing photoacoustic visualisation of clinical needles with deep learning,” in 2021 IEEE International Ultrasonics Symposium (IUS). IEEE, Sep. 2021. doi: 10.1109/ius52206.2021.9593857 [PDF]
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T. Zhao, M. T. Ma, S. Ourselin, T. Vercauteren, and W. Xia, “Towards ultrathin fiber-optic probe for simultaneous photoacoustic and fluorescence endoscopy,” in 2021 IEEE International Ultrasonics Symposium (IUS). IEEE, Sep. 2021. doi: 10.1109/ius52206.2021.9593659 [PDF]
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M. K. A. Singh and W. Xia,“Biomedical photoacoustic imaging and sensing using affordable resources,” Sensors, vol. 21, no. 7, p. 2572, Apr. 2021. doi: 10.3390/s21072572 [PDF]
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T. Zhao, S. Ourselin, T. Vercauteren, and W. Xia, “High-speed photoacoustic-guided wavefront shaping with a real-valued intensity transmission matrix,” in European Conferences on Biomedical Optics 2021. Optica Publishing Group, 2021. doi: 10.1364/ecbo.2021.em2d.1 [PDF]
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T. Zhao, S. Ourselin, T. Vercauteren, and W. Xia, “Multimode fibre-based optical-resolution photoacoustic endomicroscopy with a real-valued intensity transmission matrix,” in European Conferences on Biomedical Optics 2021 (ECBO). Optica Publishing Group, 2021. doi: 10.1364/ecbo.2021.em3d.4 [PDF]
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T. Zhao, S. Ourselin, T. Vercauteren, and W. Xia, “Focusing light through multimode fibres using a digital micromirror device: a comparison study of non-holographic approaches,” Optics Express, vol. 29, no. 10, p. 14269, Apr. 2021. doi: 10.1364/oe.420718 [PDF]
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W. Xia and M. K. A. Singh, “Biomedical photoacoustic imaging and sensing using affordable resources,” Sensors, vol. 21, no. 7, p. 2572, Apr. 2021. doi: 10.3390/books978-3-0365-1198-6 [PDF]
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T. Zhao, S. Ourselin, T. Vercauteren, and W. Xia, “High-speed photoacoustic-guided wavefront shaping for focusing light in scattering media,” Optics Letters, vol. 46, no. 5, p. 1165, Mar. 2021. doi: 10.1364/ol.412572 [PDF]
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T. Vercauteren, S. Ourselin, W. Xia, T. Zhao, “Apparatus and method for transmitting and receiving an image,” Patent GB2 591 138A, Jan. 17, 2021. [PDF]
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T. Vercauteren, S. Ourselin, W. Xia, T. Zhao, “Apparatus and method for spatial light modulation,” Patent WO/2021/144 588, Jan. 15, 2021. [PDF]
2020
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C. Schneider, D. Nikitichev, W. Xia, K. Gurusamy, A. E. Desjardins, and B. R. Davidson, “Multispectral tissue mapping: developing a concept for the optical evaluation of liver disease,” Journal of Medical Imaging, vol. 7, no. 06, Dec. 2020. doi: 10.1117/1.jmi.7.6.066001 [PDF]
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M. K. A. Singh and W. Xia, “Portable and affordable light source-based photoacoustic tomography,” Sensors, vol. 20, no. 21, p. 6173, Oct. 2020. doi: 10.3390/s20216173 [PDF]
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B. Lawton, F. Lin, S. Ourselin, T. Vercauteren, N. Desai, W. Xia “Abstracts of the trainee conference 2020: Development of an anatomically accurate ultrasound phantom for infraclavicular brachial plexus block,” Anaesthesia, vol. 75, no. S3, pp. 10–106, Jul. 2020. doi: 10.1111/anae.15157
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T. Zhao, S. Ourselin, T. Vercauteren, and W. Xia, “Seeing through multimode fibers with real-valued intensity transmission matrices,” Optics Ex- press, vol. 28, no. 14, p. 20978, Jun. 2020. doi: 10.1364/oe.396734 [PDF]
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T. Zhao, T. Vercauteren, and W. Xia, “Simple high-speed multimode fibre calibration for photoacoustic endomicroscopy (conference presentation),” in Photons Plus Ultrasound: Imaging and Sensing 2020, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Mar. 2020. doi: 10.1117/12.2550993
2019
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T. Zhao, A. E. Desjardins, S. Ourselin, T. Vercauteren, and W. Xia, “Minimally invasive photoacoustic imaging: Current status and future perspectives,” Photoacoustics, vol. 16, p. 100146, Dec. 2019. doi: 10.1016/j.pacs.2019.100146 [PDF]
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E. Maneas et al., “Photoacoustic imaging of the human placental vasculature,” Journal of Biophotonics, vol. 13, no. 4, Nov. 2019. doi: 10.1002/jbio.201900167 [PDF]
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I. Imtiaz, N. Malik, W. Xia, E. Maneas, and A. Desjardins, “Developing patient-specific carotid artery ultrasound imaging phantoms for clinical training using 3d printing,” Clinical Radiology, vol. 74, pp. e9–e10, Oct. 2019. doi: 10.1016/j.crad.2019.09.056
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Y. Xie, E. Maneas, S. Islam, W. Peveler, J. Shapey, W. Xia, S. Ourselin, I. P. Parkin, A. E. Desjardins, and T. Vercauteren, “Soft optically-tuneable fluorescence phantoms based on gel wax and quantum dots: a tissue surrogate for fluorescence imaging validation,” in Molecular-Guided Surgery: Molecules, Devices, and Applications V, B. W. Pogue and S. Gioux, Eds. SPIE, Mar. 2019. doi: 10.1117/12.2508348
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S. J. Mathews, S. Mosse, W. Xia, D. I. Shakir, Y. Kunpalin, E. Z. Zhang, P. C. Beard, S. J. West, A. L. David, and A. E. Desjardins, “Ultrasonic needle tracking with a high-finesse fabry-perot fiber optic hydrophone (conference presentation),” in Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII, A. Mahadevan-Jansen, Ed. SPIE, Mar. 2019. doi: 10.1117/12.2509670
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S. Bohndiek et al., “International photoacoustic standardisation consortium (IPASC): overview (conference presentation),” in Photons Plus Ultrasound: Imaging and Sensing 2019, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Mar. 2019. doi: 10.1117/12.2506044
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E. C. Mackle, E. Maneas, C. Little, E. Carr, W. Xia, D. Nikitichev, R. Rakhit, M. Finlay, and A. Desjardins, “Wall-less vascular poly(vinyl) alcohol gel ultrasound imaging phantoms using 3d printed vessels,” in Design and Quality for Biomedical Technologies XII, R. Liang, T. J. Pfefer, and J. Hwang, Eds. SPIE, Feb. 2019. doi: 10.1117/12.2510033 [PDF]
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D. I. Nikitichev et al., “3d printed kidney phantoms for an LED-based photoacoustic and ultrasound imaging system,” in Photons Plus Ultrasound: Imaging and Sensing 2019, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Feb. 2019. doi: 10.1117/12.2509831
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W. Xia, E. Maneas, N. T. Huynh, M. K. A. Singh, N. M. Brown, S. Ourselin, E. Gilbert-Kawai, S. J. West, and A. E. Desjardins, “Imaging of human peripheral blood vessels during cuff occlusion with a compact LED-based photoacoustic and ultrasound system,” in Photons Plus Ultrasound: Imaging and Sensing 2019, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Feb. 2019. doi: 10.1117/12.2509666
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W. Xia, S. Noimark, E. Maneas, N. M. Brown, M. K. A. Singh, S. Ourselin, S. J. West, and A. E. Desjardins, “Enhancing photoacoustic visualization of medical devices with elastomeric nanocomposite coatings,” in Photons Plus Ultrasound: Imaging and Sensing 2019, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Feb. 2019. doi: 10.1117/12.2508658
2018
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S. J. Mathews, C. Little, C. D. Loder, R. D. Rakhit, W. Xia, E. Z. Zhang, P. C. Beard, M. C. Finlay, and A. E. Desjardins, “All-optical dual photoacoustic and optical coherence tomography intravascular probe,” Photoacoustics, vol. 11, pp. 65–70, Sep. 2018. doi: 10.1016/j.pacs.2018.07.002 [PDF]
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C. Gruijthuijsen et al., “Haptic guidance based on all-optical ultrasound distance sensing for safer minimally invasive fetal surgery,” Journal of Medical Robotics Research, vol. 03, no. 03n04, p. 1841001, Sep. 2018. doi: 10.1142/s2424905x18410015 [PDF]
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W. Xia, S. J. West, M. C. Finlay, R. Pratt, S. Mathews, J.-M. Mari, S. Ourselin, A. L. David, and A. E. Desjardins, “Three-dimensional ultrasonic needle tip tracking with a fiber-optic ultrasound receiver,” Journal of Visualized Experiments, no. 138, Aug. 2018. doi: 10.3791/57207 [PDF]
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W. Xia, M. K. A. Singh, E. Maneas, N. Sato, Y. Shigeta, T. Agano, S. Ourselin, S. J. West, and A. E. Desjardins, “Handheld real-time LED-based photoacoustic and ultrasound imaging system for accurate visualization of clinical metal needles and superficial vasculature to guide minimally invasive procedures,” Sensors, vol. 18, no. 5, p. 1394, May 2018. doi: 10.3390/s18051394 [PDF]
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W. Xia, S. Noimark, E. Maneas, M. K. Singh, S. Ourselin, S. J. West, and A. E. Desjardins, “LED-based photoacoustic imaging of medical devices with carbon nanotube-polydimethylsiloxane composite coatings,” in Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS). OSA,Apr.2018. doi: 10.1364/trans- lational.2018.jw3a.4 [PDF]
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T. Zhao, L. Su, and W. Xia, “Optical ultrasound generation and detection for intravascular imaging: A review,” Journal of Healthcare Engineering, vol. 2018, pp. 1–14, Apr. 2018. doi: 10.1155/2018/3182483 [PDF]
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S. J. Mathews, C. Little, C. D. Loder, R. D. Rakhit, W. Xia, E. Z. Zhang, P. C. Beard, M. C. Finlay, and A. E. Desjardins, “All-optical intravascular probe for dual-mode photoacoustic imaging and optical coherence tomography (conference presentation),” in Photons Plus Ultrasound: Imaging and Sensing 2018, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Mar. 2018. doi: 10.1117/12.2289631
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E. Maneas, W. Xia, D. I. Nikitichev, R. Pratt, S. Ourselin, S. J. West, A. L. David, M. C. Finlay, T. Vercauteren, and A. E. Desjardins, “Patient- specific tissue-mimicking phantoms for photoacoustic and ultrasound imaging (conference presentation),” in Photons Plus Ultrasound: Imaging and Sensing 2018, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Mar. 2018. doi: 10.1117/12.2288998
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E. Maneas, W. Xia, A. L. David, S. Ourselin, T. Vercauteren, A. E. Des- jardins, M. K. A. Singh, N. Sato, T. Agano, and S. J. West, “Human placental vasculature imaging using an LED-based photoacoustic/ultrasound imaging system,” in Photons Plus Ultrasound: Imaging and Sensing 2018, A. A. Oraevsky and L. V. Wang, Eds. SPIE, Feb. 2018. doi: 10.1117/12.2288995
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E. Maneas et al., “Gel wax-based tissue-mimicking phantoms for multi-spectral photoacoustic imaging,” Biomedical Optics Express, vol. 9, no. 3, p. 1151, Feb. 2018. doi: 10.1364/boe.9.001151 [PDF]
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E. Maneas et al., “Anatomically realistic ultrasound phantoms using gel wax with 3d printed moulds,” Physics in Medicine & Biology, vol. 63, no. 1, p. 015033, Jan. 2018. doi: 10.1088/1361-6560/aa9e2c [PDF]